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Clinical immunology : principles and practice / [edited by] Robert R. Rich ... [et al.].

  • 其他作者:
  • 其他題名:
    • Clinical immunology (Rich)
  • 出版: [Amsterdam] : Elsevier 2019.
  • 主題: Immune System--physiology , Immune System Diseases--immunology , Immunity--physiology
  • 版本:Fifth edition.
  • ISBN: 9780702068966 (hbk.): NT7467 、 0702068969 (hbk.)
  • 一般註:Includes bibliographical references and index. Section 1: Principles of immune response. The human immune response -- Organization of the immune system -- Innate immunity -- Antigen receptor genes, gene products, and co-receptors -- The major histocompatibility complex -- Antigens and antigen presentation -- B-cell development and differentiation -- T-cell development -- Cytokines and cytokine receptors -- Chemokines and chemokine receptors -- Lymphocyte adhesion and trafficking -- T-cell activation and tolerance -- Regulated cell death -- The microbiota in immunity and inflammation -- Section 2: Host defense mechanisms and inflammation. Immunoglobulin function -- Helper T-cell subsets and control of the inflammatory response -- Cytotoxic T lymphocytes and natural killer cells -- Regulatory immune cells -- Host defenses in the skin -- Host defenses at mucosal surfaces -- Complement in host deficiencies and diseases -- Phagocyte deficiencies -- Mast cells, basophils, and mastocytosis -- Eosinophils and eosinophilia -- Section 3: Host defenses to infectious agents. Host defenses to viruses -- Host defenses to intracellular bacteria -- Host defenses to extracellular bacteria -- Host defenses to spirochetes -- Host defenses to fungi -- Host defenses to protozoa -- Host defenses to helminths -- Section 4: Immunologic deficiencies. Approach to the evaluation of the immunodeficient patient -- Human genomics in immunology -- Primary antibody deficiencies -- Primary T-cell immunodeficiencies -- Immunodeficiencies at the interface of innate and adaptive immunity -- Infections in the immunocompromised host -- Immune deficiencies at the extremes of age -- HIV infection and acquired immunodeficiency syndrome -- Autoantibody mediated phenocopies of primary immunodeficiency diseases -- Section 5: Allergic diseases. Immunological mechanisms of airway diseases and pathways to therapy -- Urticaria, angioedema, and anaphylaxis -- Allergic reactions to stinging and biting insects -- Atopic and contact dermatitis -- Food Section 6: Systemic immune diseases. Mechanisms of autoimmunity -- Systemic lupus erythematosus -- Rheumatoid arthritis -- Juvenile idiopathic arthritis -- Sjögren's syndrome -- Scleroderma-systemic sclerosis -- Inflammatory muscle diseases -- Spondyloarthritis -- Small and medium vessel primary vasculitis -- Large-vessel vasculitides -- Systemic autoinflammatory syndromes -- Antiphospholipid syndrome -- Section 7: Organ-specific inflammatory disease. Immunohematologic disorders -- Bullous diseases of the skin and mucous membranes -- Immunology of psoriasis -- Myasthenia gravis -- Multiple sclerosis -- Autoimmune peripheral neuropathies -- Immunologic renal diseases -- Inflammation and atherothrombosis -- Autoimmune thyroid diseases -- Diabetes and related autoimmune diseases -- Immunologic lung diseases -- Sarcoidosis -- Immunologic ocular disease -- Immunologic diseases of the gastrointestinal tract -- Inflammatory hepatobiliary diseases -- Section 8: Immunology of neoplasia. Tumor immunotherapy -- Lymphoid leukemias -- Lymphomas -- Monoclonal gammopathies -- Section 9: Transplantation. Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance -- Immune reconstitution therapy for immunodeficiency -- Hematopoietic stem cell transplantation for malignant diseases -- Section 10: Prevention and therapy of immunologic diseases. Immunoglobulin therapy: replacement and immunomodulation -- Gene therapy -- Glucocorticoids -- Immunomodulating pharmaceuticals -- Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders -- Biological modifiers of inflammation -- Vaccines -- Immunotherapy of allergic disease -- Section 11: Diagnostic immunology. Flow cytometry -- Assessment of functional immune responses -- Assessment of neutrophil function -- Assessment of human allergic diseases -- Molecular methods -- Appendices. Selected CD molecules and their characteristics -- Laboratory reference value
  • 讀者標籤:
  • 引用連結:
  • 系統號: 000284237 | 機讀編目格式

館藏資訊

Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today's latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice. User-friendly format features color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response. Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussion of translational research. Includes new multiple choice questions in every chapter online, ideal for allergists and rheumatologists seeking certification or recertification in these subspecialties. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

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